Anna Iwaniak, Kamil Dąbrowski, Małgorzata Darewicz
ABSTRACT. Computer analysis was used to evaluate the values of selected fish protein sequences as sources of biologically-active peptides. Two databases were used to analyze eight fish protein sequences: UniProt and BIOPEP. The main criterion of protein value applied was the profile of the potential biological activity of a protein. Bioinformatic analysis showed that all fish protein sequences were potential sources of bioactive peptides. The largest number of peptides detected among the analyzed fish proteins indicated an ACE inhibitory effect, which is the ability to reduce blood pressure. The best potential source of bioactive peptides was b-actin from European perch (Perca fluviatilis), while the smallest number of bioactive peptides were detected in a fragment of b-actin from freshwater whitefish (Coregonus lavaretus).
Keywords: bioactive peptides, fish protein, biological activity
Przyjęto po recenzji 16.09.2013 r.